Wednesday, March 26, 2014

Medical Benefits of Indian Saffron

Curcumin or Indian Saffron is a yellow orange dye extracted from a spice called turmeric. Medically, studies have revealed its number benefits for human health. The prime medical benefits of curcumin or Indian saffron are its anti-inflammatory, anti-oxidant and anti-cancer properties. The image below demonstrates the medical benefits of Curcumin or Indian Saffron:


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Keywords: Curcumin, Indian saffron, Haldi, Medical benefits of Indian saffron

Tuesday, March 25, 2014

Syphilis: What is the Treatment of Syphilis?



What is Syphilis?


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Syphilis is an infectious disease, caused by Treponema pallidum. It is transmitted through sexual contact, from mother to fetus or through skin contact from syphilis sore of the affected person. Typically, the patient is found to be afebrile (without fever). The lesion of primary syphilis is called chancre. Chancre presents as a single painless papule that erodes subsequently. These syphilis sores are usually found on penis, external genitalia, mouth or around the anal canal. Regional lympadenopathy is usually associated with primary lesion. Secondary syphilis presents with localized or diffused mucocutaneous rash associated with generalized non-tender lymphadenopathy. Tertiary syphilis results from prolonged inflammatory process that occurs years after the initial lesion.

What is the treatment for Syphilis?


For early lesions- treatment of choice for syphilis sore is a single intramuscular dose of Benzathine penicillin 2.4 million units. Alternative treatment for syphilis is Doxycycline 100 mg (Doxyn, Dotur), twice a day, for 14 days.
If the duration of syphilis infection is more than 14 years, intramuscular Benzathine penicillin 2.4 million units weekly are given for three weeks. Alternative treatment is Doxycycline 100 mg, twice a day, for 28 days.
Neurosyphilis is treated with intravenous Benzyl penicillin 2-4 million units, every 4 hours, for 10-14 days.

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Keywords: Syphilis disease, Syphilis treatment, Primary syphilis, Syphilis sore, Benzathine penicillin, Doxycycline 100 mg

Friday, March 14, 2014

Who is at Risk of Hepatitis B Infection?



The following groups of people should go for hepatitis B vaccination as they are at risk of hepatitis B virus infection (HBV infection):

  1. Health care professionals
  2. The patients getting blood products transfused
  3. The individuals having multiple sexual partners or unhealthy sexual behavior
  4. Drug abusers
  5. The individuals who travel to the areas with prevalent hepatitis B infection
  6. The newborns or babies who born to mothers who are carriers of HBV or with hepatitis B infection
  7. The individuals who belong to HBV prevalent areas
  8. The patients suffering from blood diatheses like sickle cell anemia or thalassemia
  9. The patients undergoing organ transplant
  10. The people who are at risk of developing chronic liver disease (CLD) such as the individuals carrying hepatitis B virus or who are alcohol abusers
  11. The patients with diabetes, chronic renal failure (CRF) and acquired immunodeficiency syndrome (AIDS)
  12. The individuals who use the utensils of the patients with HBV infection
  13. The persons exposed to HBV infection like policemen, fire-brigade personnel or army personnel

Hepatitis B vaccination schedule (Engerix-B) comprises of three injections to be injected into muscles at 0, 1, 6 months OR 0, 1, 2 months. However, for 0, 1, 2 months schedule, fourth dose is recommended at 12 month. Adult dose of HBV vaccine 20 micrograms (1 ml suspension).

Keywords: Who is at risk of HBV, Hepatitis B vaccination schedule, HBV infection, Hepatitis B vaccination,Who should get hepatitis B vaccination?, Engerix-B

Monday, March 10, 2014

Depilus Cream: A Hair Removal Cream

What is Depilus cream?

Depilus cream is used to treat hirsutism or to remove facial hairs. In other words, it is a hair removal cream. It contains a substance called eflornithine hydrochloride that slows or decreases the abnormal hair growth (hair removal cream). Depilus cream is applied to the affected area of the face or the other parts of the body. Depilus cream is used to remove excessive hair, especially in the patients with polycystic ovarian syndrome (PCO).
Depilus Cream 13.9% (Eflornithine hydrochloride)


What is the mechanism of action of Depilus cream?

It reduces follicular cell growth rate and slows down the hair growth. Eflornithine inhibits an enzyme named ornithine decarboxylase (ODC) present in the human skin and catalyses the biosynthesis of polyamines necessary for cell growth.


How to use Depilus cream: Check the video below

How Depilus is packed? Check video below.

What are indications of Depilus cream?

Depilus cream (Eflornithine HCL) is indicated in women with unwanted facial hair.

How to use Depilus cream?

To use Depilus cream, wash your mouth, dry it and then apply the cream gently two times a day. Wash your mouth after 4 hours. To get best results, massage a thin layer of the cream on chin, upper lip or other affected areas of face.

How long it takes to see improvement of hair removal?

It takes 4-8 weeks to see the improvement in hair removal. However, hair may regrow after the discontinuation of the treatment. It is not a depilatory preparation, but improves patient's appearance by reducing hair growth.

Can I use Depilus cream along with cosmetics, moisturizers and sunscreens?

Yes, Depilus cream can be used along with other cosmetics, moisturizers and sunscreens. You can apply Depilus cream first and wait till it dries before applying other skin products.

What are the side effects of Depilus cream?

Depilus or Eflornithine cream may cause side effects like acne, burning or tingling of the skin, stinging sensation, skin rash or swollen skin patches.

What are the precautions for Depilus cream usage?

Store it at room temperature (below 30 centigrade); keep it away from children; do not swallow it as it is only for external use; keep it in the container it comes packed in; avoid extreme heat, light or moisture; do not freeze it and avoid high doses.

Can children and the elderly people use Depilus cream?

For children below 12 years of age, the safety and effectiveness of Depilus (Eflornithine HCL) have not been established yet. However, in geriatrics, no apparent difference of safety and effectiveness has been observed.

Can topical eflornithine hydrochloride be used in addition to laser hair treatment?

Yes, studies have shown that topical use of eflornithine HCL enhances the hair removal and reduces inflammatory papules. Eflornithine HCL reduces follicular cell growth rate while laser hair treatment suspends hair growth by heating the hair and surrounding tissues.

What are the contraindications of Depilus cream use? 

It should not be used during pregnancy and lactation. Also, it is contraindicated for those patients with known hypersensitivity to Depilus cream.

What is the price of Depilus cream?

The price of Depilus cream (15 grams laminated flexible tube) is Rs. 780.

In what brands Eflornithine is available?

Depilus cream, Eflogen, Epila, Vaniqa cream

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Keywords: Depilus cream, Eflornithine cream, ornithine decarboxylase, hair removal cream, side effects of Depilus cream, Remove facial hair, How to use Depilus cream, Contraindications, Vaniqa cream, Epila, Eflogen

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