IV Paracetamol in Pediatrics

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Being an effective analgesic and antipyretic, the use of IV paracetamol is on the rise in pediatrics. Paracetamol inhibits cyclooxygenase-2 (COX-2) enzyme and reduces the production of prostaglandins (PGs). It is safe to offer the post-operative analgesia in children. Hepatotoxicity is rare with prescribed doses and it only occurs when sustained high doses of paracetamol (>90 mg/kg/day) are given.

For more reading, visit the following comprehensive review: REVIEW ARTICLE – Intravenous paracetamol in pediatrics: A global perspective 

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Key words: Intravenous Paracetamol, IV paracetamol, Acetaminophen, Analgesic, Antipyrectic, Children, Pediatrics